Glycopyrrolate+formoterol Fumarate+fluticasone Propionate
About Glycopyrrolate+formoterol Fumarate+fluticasone Propionate
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate belongs to the class of respiratory stimulants primarily used to prevent and treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD), such as shortness of breath or wheezing (whistling sound while breathing). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate is a combination of three drugs, namely: Glycopyrrolate (anticholinergic), Formoterol fumarate (bronchodilator), and Fluticasone propionate (corticosteroid). Glycopyrrolate decreases the secretions in the airways. Formoterol fumarate belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. This makes breathing easier. Fluticasone propionate is a corticosteroid that works by acting on cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby providing relief from asthma and COPD.
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate is for inhalation only. Use Fluticasone Propionate+formoterol Fumarate+glycopyrrolate as prescribed. You are advised to use Fluticasone Propionate+formoterol Fumarate+glycopyrrolate for as long as your doctor has prescribed it based on your medical condition. Some people may experience headache, sore throat, stuffy nose, chest tightness, dry mouth, and constipation. Most of these side effects of Fluticasone Propionate+formoterol Fumarate+glycopyrrolate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Fluticasone Propionate+formoterol Fumarate+glycopyrrolate or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before using Fluticasone Propionate+formoterol Fumarate+glycopyrrolate. Fluticasone Propionate+formoterol Fumarate+glycopyrrolate is not recommended for children below 1 year of age. If you experience severe difficulty breathing, please consult a doctor immediately so that alternative medicine may be prescribed. Regular monitoring of potassium levels is recommended while taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate as it may cause low potassium levels in the blood.
Uses of Glycopyrrolate+formoterol Fumarate+fluticasone Propionate
Medicinal Benefits
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate contains Glycopyrrolate, Formoterol fumarate and Fluticasone propionate. Glycopyrrolate decreases the secretions in the airways. Formoterol fumarate relaxes muscles and widens the airways of the lungs. Thus, makes breathing easier. Fluticasone propionate acts on cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from asthma and COPD.
Directions for Use
Storage
Side Effects of Glycopyrrolate+formoterol Fumarate+fluticasone Propionate
- Headache
- Sore throat
- Stuffy nose
- Chest tightness
- Dry mouth
- Constipation
Drug Warnings
If you are allergic to Fluticasone Propionate+formoterol Fumarate+glycopyrrolate or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before using Fluticasone Propionate+formoterol Fumarate+glycopyrrolate. Fluticasone Propionate+formoterol Fumarate+glycopyrrolate is not recommended for children below 1 year of age. If you experience severe difficulty in breathing, please consult a doctor immediately so that an alternative medicine may be prescribed. Contact your doctor if you have blurred vision or any other vision disturbances while taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate. Regular monitoring of potassium levels is recommended while taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate as it may cause low potassium levels in the blood.
Drug Interactions
Drug-Drug Interaction: Fluticasone Propionate+formoterol Fumarate+glycopyrrolate may interact with bronchodilators (salbutamol, aminophylline, theophylline), steroids (budesonide, prednisone, mometasone, beclometasone), heart-related medicines (sotalol, digoxin, disopyramide, procainamide, quinidine), drugs used to treat Hodgkin’s disease (procarbazine), water pills (furosemide), antibiotics (telithromycin, furazolidone, clarithromycin), drugs used to lower high blood pressure (atenolol, metoprolol, propranolol), medicines to induce labor (oxytocin), antithyroid agent (levothyroxine), antidepressants (imipramine, amitriptyline, isocarboxazid, phenelzine), antifungals (itraconazole, ketoconazole), HIV medicines (atazanavir, ritonavir, nelfinavir, indinavir, cobicistat, saquinavir) and antiparkinson drug (levodopa).
Drug-Food Interaction: Fluticasone Propionate+formoterol Fumarate+glycopyrrolate may interact with grapefruit and grapefruit juice. Therefore, avoid intake of grapefruit or its juice with Fluticasone Propionate+formoterol Fumarate+glycopyrrolate as it may lead to severe adverse effects.
Drug-Disease Interaction: If you have high blood pressure, diabetes, chest or lungs infection, hyperthyroidism (overactive thyroid), hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), tuberculosis, heart, liver, or adrenal gland problems, inform your doctor before taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThe interaction of Fluticasone Propionate+formoterol Fumarate+glycopyrrolate with alcohol is unknown. Please consult a doctor before consuming alcohol with Fluticasone Propionate+formoterol Fumarate+glycopyrrolate.
Pregnancy
cautionFluticasone Propionate+formoterol Fumarate+glycopyrrolate is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Therefore, inform your doctor if you are pregnant before taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate.
Breast Feeding
cautionIt is unknown whether Fluticasone Propionate+formoterol Fumarate+glycopyrrolate is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.
Driving
safe if prescribedFluticasone Propionate+formoterol Fumarate+glycopyrrolate usually does not affect your ability to drive or operate machinery.
Liver
cautionUse Fluticasone Propionate+formoterol Fumarate+glycopyrrolate with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionUse Fluticasone Propionate+formoterol Fumarate+glycopyrrolate with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionFluticasone Propionate+formoterol Fumarate+glycopyrrolate is not recommended for children below 1 year of age. However, please consult a doctor before giving Fluticasone Propionate+formoterol Fumarate+glycopyrrolate to children.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
- Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.
- Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
- Quit smoking as it may reduce the effectiveness of the Fluticasone Propionate+formoterol Fumarate+glycopyrrolate and irritate the lungs worsening breathing problems.
- Learning breathing exercises will help you move more air in and out of your lungs.
Special Advise
Regular monitoring of blood sugar levels is recommended while taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate especially if you have diabetes as it may increase blood sugar levels.
Patients Concern
Disease/Condition Glossary
Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The asthma treatment includes medication, breathing exercises, and self-care.
Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).
FAQs
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate works by relaxing muscles and widening the airways of the lungs. Also, it stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose, sinus discomfort and makes breathing easier.
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate to experience this side effect. However, to avoid such side effects, drink plenty¬ of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take sotalol with Fluticasone Propionate+formoterol Fumarate+glycopyrrolate as it may reduce the effectiveness of both medicines. Also, sotalol may trigger asthma attacks or worsen breathing problems by narrowing airways. However, please consult a doctor before using other medicines with Fluticasone Propionate+formoterol Fumarate+glycopyrrolate.
You are not recommended to take more than the prescribed dose of Fluticasone Propionate+formoterol Fumarate+glycopyrrolate as it may cause adverse effects such as muscle cramps, headache, high or low blood pressure, fits, severe chest pain, dry mouth, difficulty in sleeping, loss of appetite, nausea, tiredness, shaking or light-headedness. However, if you experience any of these symptoms while taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate, please consult a doctor immediately.
You are not recommended to stop taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Fluticasone Propionate+formoterol Fumarate+glycopyrrolate for as long as your doctor has prescribed it and if you experience any difficulty while taking Fluticasone Propionate+formoterol Fumarate+glycopyrrolate, please consult your doctor.
Fluticasone Propionate+formoterol Fumarate+glycopyrrolate does not relieve a sudden asthma attack. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.
